Two Cases of Nasopharyngeal Mucosal Malignant Melanoma

Korean Journal of Head & Neck Oncology 1995;11(1):24-29.
Published online June 30, 1995.

Ji Youn Han;Min Sik Kim;Hong Seok Jang;Hoon Kyo Kim;Young Seon Hong;Kyung Shik Lee;Dong Jip Kim;Young Hak Park;Seung Ho Cho;Byung Do Seo;Sei Chul Yoon

비인강 점막성 악성흑색종 2예

한지연;김민식;장홍석;김훈교;홍영선;이경식;김동집;박영학;조승호;서병도;윤세철

Abstract

Melanoma of the mucous membrane is a rare condition and has the worse prognosis than that of any other sites. It is usually asymptomatic in early stage and difficult to find out the primary lesion by visual examination, and these facts lead to delay in diagnosis and reduce the curability. The major factor of failure in treatment of melanoma is local recurrence rather than regional spread. Because the radical procedure is difficult in head and neck lesion due to anatomical limitation, radiation therapy and chemotherapy can be used in the treatment of local recurrence. We experienced two cases of nasopharyngeal melanoma in advanced stage and treated them with radiation therapy and/or chemotherapy. And both patients showed relatively favorable response to these palliative treatments.

Key Words: Melanoma, Nasopharynx