| The Evaluation of the Clinical Features and the Results of Treatment of Localized Head and Neck Malignant Lymphoma |
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Ji Youn Han;Byung Gil Choi;Min Sik Kim;Hong Seok Jang;Hoon Kyo Kim;Young Sun Hong;Kyung Shik Lee;Dong Jip Kim;Young Hak Park;Seung Ho Cho;Byung Do Seo;Sei Chul Yoon;Kyu Ho Choi |
| 국소성 두경부 악성 임파종의 임상적 특징 및 치료 성적 분석 |
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한지연;최병길;김민식;장홍석;김훈교;홍영선;이경식;김동집;박영학;조승호;서병도;윤세철;최규호 |
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| Abstract |
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Localized non-Hodgkin's lymphomas of head and neck are generally treated with radiation therapy with or without chemotherapy and the results of treatments are favorable, but the recurrences in the primary site or distant sites are a major contributor to failure, We experiened 19 cases of localized non-Hodgkin's lymphomas for 4-year period and retrogradely analized them. We treated patients with Ann Arbor stage I and low grade histology in Working formulation with radiation therapy and patients with Ann Arbor stage II, moderate to high grade histology or extensive tumor size with combination chemotherapy, The complete responses were occurred in 15 of 19 patients (radiation therapy, 5/6 (83.3%); chemotherapy 10/13(76.9%)). 3 relapses were occurred; 2 were in local relapses and 1 was in distant leptomeningeal relapse and the counter-therapeutic modalities were successful in 2 cases. Our results suggest that Ann Arbor stage is significant prognostic factor and appropriate staging with extensive methods is important to improve the results of treatment. |
| Key Words:
Lymphoma, Head and Neck |
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