Patterns of Failure According to Radiation Treatment Technique in the Parotid Gland Cancer |
Sang wook Lee;Chang Geol Lee;Ki Chang Keum;Cheong Soo Park;Eun Chang Choi;Hyun Soo Shin;Sung Sil Chu;Suk Lee;Kwang Hwan Cho;Chang Ok Suh;Gwi Eon Kim |
이하선암의 술후 방사선치료시 방사선치료 방법에 따른 치료 실패 양상 분석 |
이상욱;이창걸;금기창;박정수;최은창;신현수;추성실;이석;조광환;서창옥;김귀언 |
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Abstract |
Objectives: To compare the outcomes of treatment with a focus on the effectiveness of the two primary techniques of radiation used for treating parotid gland malignancies.
Materials and Methods: A retrospective analysis of 70 patients with parotid gland cancer treated between 1981-1997. Radiation was delivered through an ipsilateral field of high energy electron and photon in 37 patients(52.9%). Two wedge paired photon was used to treat in 33 patients(47.1%). The median dose was 60 Gy, typically delivered at 1.8-2.0Gy per fraction. The median follow-up times for surviving patients was 60 months.
Results The overall and disease free 5 year survival rates were 71.6% and 69.5%, respectively. Wedge paired photon and photon-electron treatment disease tree 5 year survival rates were 61.1% and 80.5%, respectively. Overall local failure rate was 18.6%. Local failure rate of wedge paired photon technique was higher than that of mixed beam technique. Late complication rate was 37.1%, but most of them were mild grade.
Conclusion Techniques of radiation were associated with local control. The technique of using an ipsilateral field encompassing the parotid bed and treated with high energy electrons often mixed photons was effective with minimal severe late toxicity. To irradiate deep sited tumors, we consider 3-D conformal treatment plan for well encompassing the target volume. |
Key Words:
Radiotherapy technique, Parotid gland cancer |