Treatment Results for Adenoid Cystic Carcinoma of the Major Salivary Gland

Korean Journal of Head & Neck Oncology 2002;18(2):197-202.
Published online November 30, 2002.

Sang wook Lee;Gwi Eon Kim;Cheong Soo Park;Eun Chang Choi;Kang Kyoo Lee;Won Park;Chang Ok Suh

주타액선에서 발생한 선양낭세포암종의 방사선치료성적

이상욱;김귀언;박정수;최은창;이강규;박원;서창옥

Abstract

Purpose
This study was to investigate clinical feature of adenoid cystic carcinoma (ACC) in the major salivary gland. Materials and Methods: A retrospective analysis was undertaken for 23 patients with adenoid cystic carcinoma of the major salivary gland, who completed postoperative radiotherapy at the Yonsei Cancer Center, Yonsei University Hospital between May 1981 and December 1999. The male to female ratio was 1.1:1. Median age was 50. Follow up periods were 12-180 months with the median follow-up time of 59 months.
Results
Parotid gland, submandibular gland and sublingual gland were 17, 5 and 1 respectively. Overall failure rate was 26%. Local failure was observed in two patients with parotid gland origin. Five cases showed distant failure. Overall and disease free survival rate were 68% and 72% respectively.
Conclusion
Major pattern of failure was distant failure. Resection margin status had not prognostic significance. Postoperative radiation treatment is an effective to control in the adenoid cystic carcinoma of the major salivary gland.

Key Words: Parotid gland, Adenoid cystic carcinoma, Radiation treatment