Granular Cell Tumor in the Lower Lip：A Case Report

Korean Journal of Head & Neck Oncology 2009;25(1):33-35.
Published online May 30, 2009.

Gi Yeun Hur;Suk Joon Oh;Sung Hoon Koh;Jeongho Cha;Kwang Seon Min

하구순의 과립세포종 증례보고

허지연;오석준;고성훈;차정호;민광선

Abstract

Purpose
：Granular cell tumour(GCT) is a rare benign tumour that can arise in anywhere throughout the body. Histopathological diagnosis of malignancy is difficult. We report a case of a granular cell tumor which developed on lower lip.
Methods
：A 58-year-old male had a palpable mass and whitish plaque in the oral mucosa for three months.
Results
：Under local anasthesia, the tumor was removed through wide excision including normal skin mar-gin. Immediate reconstruction using local flap was done. Pathologic observation showed nests of polygonal cells with abundant granular, eosinophilic cytoplasm and round nuclei. Immunohistopathologic staining showed posi-tive reaction on S-100 protein
Conclusion
：The results support the hypothesis that granular cell tumor is derived from Schwann cells. We report here on a case of granular cell tumor of lower lip that was successfully treated with radical resection.

Key Words: Lip tumor, Granular cell tumor, Schwann cell