Korean J Head Neck Oncol Search

CLOSE


Korean Journal of Head & Neck Oncology 2009;25(2):123-127.
Published online November 30, 2009.
Immunohistochemistry of CK7, CK19, CK20, SMA and Ki-67 Expression in Adenoid Cystic Carcinoma of the Head and Neck
Young Eun Moon;Woo Jin Jeong;Dong Wook Lee;Hyung Geun Song
두경부 영역에 발생한 선양낭성암종에서 CK7, CK19, CK20, SMA 및 Ki-67의 발현에 관한 면역조직화학적 연구
문영은;정우진;이동욱;송형근
Abstract
Objectives :The aim of this study was to investigate immunohistochemical expression of CK7, CK19, CK20, SMA and Ki-67 in Adenoid cystic carcinoma(ACC) of the Head and Neck. Material and Methods :Sixteen patients who were treated in Chungbuk National University Hospital from 1992 to 2004, were included in this study. Ten ACCs, 3 MECs, 1 Salivary duct carcinoma, 1 Adenocarcinoma(NOS), and 1 cacinoma ex pleomorphic adenoma were analyzed immunohistochemically for CK7, CK19, CK20, SMA, and Ki-67. Results :CK7 was expressed in 100% of the adenoid cystic carcinoma and 75% of the other tumors. CK19 was expressed in 75% of the adenoid cystic carcinoma and 100% of the other tumors. CK20 was not expressed in all tumors. SMA was expressed in 88.9% of the adenoid cystic carcinoma and not expressed in the other tumors. Ki-67 was expressed in low level in the adenoid cystic carcinoma. Conclusion :The Ki-67 index could explain the natural course of tumor. Immunohistochemistry of CK7, CK19, CK20, SMA and Ki-67 expression in Adenoid cystic carcinoma may provide useful information to diagnosis.
Key Words: Adenoid cystic carcinoma, Immunohistochemical staining, Head and neck


ABOUT
ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES
EDITORIAL POLICY
AUTHOR INFORMATION
Editorial Office
123, Jeokgeum-ro, Danwon-gu, Ansan-si, Gyeonggi-do 15355, Republic of Korea
Tel: +82-31-412-6879    Fax: +82-31-412-5174    E-mail: kshno@hanmail.net                

Copyright © 2021 by Korean Society for Head & Neck Oncology. All rights reserved.

Developed in M2PI

Close layer
prev next