A Case Report of Eosinophilic Granuloma in the Frontal Bone

Korean Journal of Head & Neck Oncology 2010;26(2):243-246.
Published online November 30, 2010.

Seung Hyun Shim;Chul Hoon Chung;Yong Joon Chang

전두골에 발생한 호산구성육아종의 치험례

심승현;정철훈;장용준

Abstract

Purpose
：Eosinophilic granuloma is a rare benign tumor that is characterized histologically by the presence of destructive granulomas containing numerous Langerhans, cells. The most common presentation of eosino-philic granuloma is a painful, immobile scalp mass in the frontal and parietal bones occurring predominantly in children and adolescents or young adults. We report a representative case of eosinophilic granuloma. Meth -ods ：A 16-year-old woman complained of an enlarging fixed scalp mass without pain and tenderness which mea-sured 3×4.5cm at the frontal area, which had been found incidentally 2 months before. Plain skull x-ray showed a punched-out bone lesion. Computed tomography and magnetic resonance imaging showed a non-enhancing oste-olytic lesion. The tumor and surrounding bony edges were completely removed via a bicoronal approach. The bony defect was reconstructed with bone cement. Results ：The tumor was involved frontal bone and dura mater. We confirmed the tumor by the documentation of Birbeck’s granules by electron microscopy. There is no evidence of local recurrence during postoperative 1.5 years. Conclusion ：The present case shows the characteristic fea-ture of frontal bone involvment of the eosinophilic granuloma. The prognosis of eosinophilic granuloma depend on age at diagnosis and number of bones involved. We consider that best choice of treatment for eosinophilic gra-nuloma is surgical excision.

Key Words: Eosinophilic granuloma