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Korean Journal of Head & Neck Oncology 2017;33(2):81-84.
Published online November 30, 2017.
A case of Langerhans cell histiocytosis involving the cervical lymph node
Youn Tae Seo;Ho Jin Son;Gyu Ho Jang;Jeong Kyu Kim
경부 임파선을 침범한 랑게르한스 세포 조직구증 1예
서윤태;손호진;장규호;김정규
Abstract
Langerhans cell histiocytosis (LCH) is a heterogeneous disease, characterized by accumulation of dendritic cells with features similar to epidermal Langerhans cells. It is a rare entity that may involve various organ levels such as the skeletal, pulmonary, hematopoietic and lympho-vascular systems. The patient was a 1-year-old female presented with fever associated with otorrhea and palpable cervical lymph node for 4 days. Neck ultrasonography and Computed tomography imaging revealed multiple enlarged lymph nodes suggesting suspicious malignant morphology. Lymph node biopsy was performed under general anesthesia. Histological and immunophenotypic examination showed the lymph node to be consistent with LCH. The patient was given chemotherapy.
Key Words: Langerhans cell histiocytosis, Lymphadenopathy, Ultrasonography


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