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Korean Journal of Head & Neck Oncology 2000;16(2):182-186.
Published online November 30, 2000.
The Efficacy of Preincisional Surgical Site Infiltration of Ketorolac & Bupivacain in Minimally Invasive Thyroid Surgery: A Double Blind Study
Woung Youn Chung;Tae Jin Kim;Hae Kyung Lee;Cheong Soo Park
최소침습 갑상선절제술에서 피부절개전 Ketororac과 Bupivacaine 국소주사에 의한 진통효과
The reduction of the postoperative wound pain has been a concern in recent surgery, especially in various types of minimally-invasive surgeries. This study was performed to evaluate the postoperative analgesic effect of the preincisional local anesthesia with the mixture of ketorolac(Tarasyn) and bupivacaine to the surgical site in minimally-invasive thyroid surgeries. Of 491 patients who were scheduled for minimally-invasive thyroid surgeries between October 1999 and July 2000, 244 were randomly assigned to receive a mixture of ketorolac tromethamine 15mg(0.5ml) and 0.25% bupivacaine 3ml via surgical site infiltration 3 minutes prior to the skin incision. The outcomes of these patients were compared to those of the 247 controls. Total number of patients in need of post-operative analgesic requirements(n=39, 16.0%), total dose of postoperative analgesics used(19.6±8.4mg of ketorolac) and Visual Analogue Pain Score(VAS, 2.6±1.2) of the preincisional local anesthesia group were significantly lower than those of the control group(p 1.6±0.4 days for the preincisional local anesthesia group versus 1.9±0.7 days for the control group. The preincisional local infiltration of ketorolac and bupivacaine in the minimally invasive thyroidectomies reduces postoperative wound pain thus would be more beneficial to the patients.
Key Words: Minimally invasive thyroid surgery, Ketorolac, Bupivacaine, Preincisional infiltration
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