Korean J Head Neck Oncol Search


Korean Journal of Head & Neck Oncology 2008;24(2):174-178.
Published online November 30, 2008.
A Clinical Analysis of Peripheral Nerve Sheath Tumors in the Head and Neck Region
Seok Young Kang;Myung Chul Shin;Han Seok Yoo;Yong Seop Lee;Chul Won Park;Kyung Tae
두경부 말초신경초종의 임상적 고찰
강석영;신명철;유한석;이용섭;박철원;태 경
Background and Objectives :Peripheral nerve sheath tumors(PNSTs) are uncommon neoplasm in the head and neck region. The treatment of PNSTs is surgical removal, but excision cause neurologic complications. This study was performed to evaluate the proper diagnosis and treatment of PNSTs with our experiences. Subjects and Method :During the period from October 1994 to July 2007, 58 patients were diagonised with PNSTs in head and neck region. We reviewed medical records and imaging study retrospectively. Result :95%(55/58) of the PNSTs in head and neck were benign;5%(3/58) were malignant peripheral nerve sheath tumors(MPNSTs). 63%(37/58) were neurilemoma, 20%(17/20) were neurofibroma, 2%(1/58) was perineuroma. 55 patients underwent surgery. 80%(45/55) of cases were treated with excision. Enucle-ation was performed in 7(14%) patients. All cases of benign neurogenic tumors showed no recurrence. Among 3 of MPNSTs 2 patients were Von Recklinghausen’s disease and expired with regional recurrence and lung metastasis.
:The benign PNSTs can be treated with enucleation if possible and observation can be another choice to minimize neurologic sequele.
Key Words: Neurilemoma, Neurofibroma, Peripheral nerve sheath tumor


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