A Case of Malignant Peripheral Nerve Sheath Tumor with Hypopharyngeal Cancer

Korean Journal of Head & Neck Oncology 2012;28(1):37-41.
Published online May 30, 2012.

Sang Ho Lim;Kyung Seok Lee;Yoon Soo Yang;Ki Hwan Hong

하인두암과 동반된 경부의 악성 말초 신경초종 1예

임상호;이경석;양윤수;홍기환

Abstract

The malignant peripheral nerve sheath tumor(MPNST) is an extremely rare soft tissue sarcoma of ectomes-enchyme also known as malignant schwannoma or malignant neurilemoma. It is a highly malignant sarcoma, which is locally invasive, frequently leading to multiple recurrences and eventual metastatic spread. The peak incidence of this disease is known to arise in the seventh decades. In human body, trunk and extremities are the most commonly involved sites, and only 8-14% of all lesions appear in head and neck region. Because immu-nohistochemical staining is essential in final diagnosis. The authors report a case of malignant peripheral nerve sheath tumor in neck with hypopharyngeal cancer simultaneously on a review of the literature.

Key Words: .Malignant peripheral nerve sheath tumor(MPNST), Hypopharyngeal cancer