Korean J Head Neck Oncol Search


Korean Journal of Head & Neck Oncology 1991;7(2):114-119.
Published online December 30, 1991.
A Case of Malignant Oncocytoma of the Parotid Gland
Yong Jin Park;Young Pyo Suh;Min Sik Kim;Seung Ho Cho;Byung Do Suh
이하선에 발생한 악성 타액선 호산성 과립세포종 1례
Malignant oncocytoma(oxyphil cell adenoma) is a extremely rare malignant tumor of the salivary glands and almost occurs in the parotid gland. A case of malignant oncocytoma of the parotid gland occurring in a 63 year old man is reported. Establishing a diagnosis of malignant oncocytoma essentially requires the application of two sets of criteria to the tumor under examination. First, the tumor cells must be identified as oncocyte and second, malignancy must be determined. Histochemical stains are not as useful as generally believed. Electron microscopy confirms the diagnosis by demonstrating an abundance of mitochondria. The diagnosis of malignant oncocytoma depends on several additional criteria in addition to cellular and nuclear pleomorphism, including lack of encapsulation, local infiltration, perineural and intravascular growth, and regional and/or distant metastasis. Satisfactory results from surgical resection and postoperative radiotherapy in our patient serve as additional experience in the treatment of this rare malignancy.
Key Words: Malignant oncocytoma, Parotid gland, Radical parotidectomy


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